CDX2 and breast carcinoma: Furthermore, the presence of VDR genetic variants was not correlated with breast cancer risk [52], although several studies evaluating the role of VDR polymorphisms in the context of cancer development revealed that FokI, BsmI, TaqI, ApaI and Cdx2, the main polymorphisms of VDR gene may contribute to influence breast cancer risk [106,107,108,109].