When the biochemical markers were evaluated it was found that the WBC, NLR, SIRI, PLR, PCT, CRP and hepcidin levels of the severe AP group were significantly increased compared to the mild AP group (p < 0.001 for NLR, SIRI, CRP and hepcidin; p < 0.01 for PLR and PCT). This evidence concerns the gene CRP and alkaline phosphatase measurement.