They observed that the WBC ≥ 23 × 103/μL was associated with severe AP, with significant differences between the three degrees of severity, and the same was verified for CRP (≥200 mg/L) and PCT (≥10 U/L), however, to this last biomarker, the average levels did not differ significantly for the severity of AP. Here, CRP is linked to alkaline phosphatase measurement.