Similarly to Parkinson’s and Alzheimer’s patients [44,45], in which an increased concentration of TGFB1 was found in the cerebrospinal fluid (CSF) or serum respectively, TGFB1 plasma concentration in ALS patients is significantly higher than in the healthy controls, and it positively correlates with the disease [46]. This evidence concerns the gene TGFB1 and amyotrophic lateral sclerosis.