Indeed, by examinating the effects of EBV infection on proinflammatory cytokines secretion by NPC cells after Zn-BC-AM PDT, they showed that a light dose of 0.25–0.5 J/cm2 on Zn-BC-AM PDT-treated HK-1-EBV cells induce a higher level of IL-1α and IL-1β secretion than the non-treated HK-1 cells. The gene discussed is IL1A; the disease is nasopharyngeal carcinoma.