For instance, cisplatin (CDDP) has been shown to reduce the number of myeloid-derived suppressor cells in a murine B16 melanoma model [18], while another study reported that CDDP can sensitize tumor cells to Fas-mediated tumor cell killing by enhancing Fas expression on tumor cells, thereby increasing their vulnerability to immune cells expressing Fas ligand [19]. Here, FASLG is linked to neoplasm.