Indeed, a high liver content of Cer(d18:1/22:0) and Cer(d18:1/24:0) might prevent hepatic steatosis under fat overload conditions by reducing peroxisome proliferator-activated receptor γ2 content and, as a consequence, reducing CD36 and FSP27 gene expression [45]. This evidence concerns the gene CD36 and Hepatic steatosis.