Exceptions were higher blood pressures in CSE−/− mice compared to WT (measured here under light anesthesia, noting that the this strain of CSE−/− mice is reported to be normotensive when conscious [27]) We also observed markedly higher atrial Mir21a expression levels and slightly lower ventricular expression of Casp3, Ace, and Nrf2 in CSE−/− mice compared to their WT comparator groups, especially after infarction. Here, ACE is linked to infarction.