DACT1 and mucinous ovarian cancer: Dapper1 Antagonist of Catenin-1 (DACT1), an inhibitor of β-catenin, is underexpressed in EOC cell lines and tissue samples [87], and overexpressing DACT1 in a mucinous ovarian cancer cell line leads to smaller tumors in vivo, as well as significantly lower levels of critical mediators of the Wnt pathway, including DVL2, β-catenin, and phosphorylated GSK-3β [87].