MUPP and hepatocellular carcinoma: Dow et al. [28] utilized genomics and transcriptomic profiles to determine human relevance of four different etiological models of murine HCC: the Stelic Animal Model (STAM), liver-specific TAK-1 deficient mice, MUP transgenic murine model, and carcinogen-driven diethylnitrosamine (DEN)-induced HCC.