BRD2 and epilepsy: Although it is thought that aging results from the cumulative effects of molecular and cellular damage, we serendipitously discovered that a Brd2-haploinsufficient (Brd2+/-; denoted HET) mouse model we developed to study epilepsy [1–3] had a much longer lifespan compared to wild type (Brd2+/+; denoted WT) mice.