Integrin α2 (ITGA2) as a number of α subunit family combines with beta 1 subunit of the α2β1 integrin to form the heterodimer. Accumulating studies demonstrated that the ITGA2 was connected with the proliferation, invasion and metastasis of various cancers, such as gastric cancer14 and glioblastoma.15 Here, ITGA2 is linked to glioblastoma.