Of these genes, 4 (DNAJC6 [PARK19], SYT11, SNAP91 [AP180], EPS15) showed enrichment involving synaptic vesicle formation and recycling, with DNAJC6 and SYT11 previously associated with PD.46, 47, 48, 49, 50. This evidence concerns the gene EPS15 and Parkinson disease.