APP or J20 mice expressed a human variant of APP containing the Swedish (K670N/M671L) and Indiana (V717F) familial Alzheimer's disease linked mutations, in neurons and oligodendrocytes (Figure S1), driven by the platelet‐derived growth factor‐beta chain (PDGF‐β) promotor (Mucke et al., 2000). This evidence concerns the gene APP and early-onset autosomal dominant Alzheimer disease.