LCN2 and acute kidney injury: A meta-analysis of 2538 patients revealed that AUC-ROC of NGAL for predicting AKI across all settings was 0.83 (95% CI, 0.74–0.91) when a median cut-off value of > 150 ng/mL and common creatinine-based definition of AKI (defined as Cr increase > 50% within 7 days) were used [4, 35, 36].