Aforced animal training platform has been proven to have a positive effect on strokeprevention (5,25), while showing no obvious effects on stroke rehabilitation (8,16).It was suggested that brain damage can be reduced through physical activity before astroke, attributable to angiogenesis and neurotrophin overexpression in brainregions supplied by the MCA following treadmill workout (25). The gene discussed is BDNF; the disease is Stroke.