This study was designed to retrospectively evaluate autoAbs against TPO, DSG1, DSG3 and both muscarinic receptor 3 (M3) and nicotinic alpha (n) AChR in patients with diagnosed pemphigus vulgaris (PV) or pemphigus foliaceus (PF) and to correlate anti-TPO and anti-AChR titer levels with anti-DSG Abs, disease course, and medication regimen. The gene discussed is TPO; the disease is pemphigus vulgaris.