Only a few genes showed opposite expression trends in the two groups: LGALS7) was elevated in KJ but decreased in KC, while 12 genes (CD34, CHST6, COLGALT2, DKK2, KDR, KERA, MAMDC2, MME, NANOS, PDGFD, RECK, STEAP4) were decreased in KJ and increased in KC. This evidence concerns the gene DKK2 and keratoconus.