PTEN and neoplasm: In ovarian cancer, mutation of PTEN has been a reported driver in endometrioid and clear cell subtypes.6–10 Homozygous loss of PTEN is found in 6% of HGSOC11 and loss-of-function mutations of Pten allow for accelerated tumour growth in mouse and in vitro models of HGSOC and ENOC.12–14 We previously demonstrated that PTEN loss is prevalent in HGSOC using bioinformatics and image analysis methods that corrected for cellularity in gene expression signatures from The Cancer Genome Atlas.15PTEN and AR gene expression were significantly correlated and had positive survival effects.