In addition, based on available bioenergetic data, the percentage of active mitochondria, between WT and PINK1-KO and before/after psychological distress, is likely similar for all of the various experimental groups and conditions, given that the percentage of OCR required to produce ATP (ATP-dependent OCR) in PINK1-KO-PBMCs is approximately 40% higher as in WT-PBMCs (Fig. 2), regardless of whether animals were exposed to psychological distress. This evidence concerns the gene PINK1 and Abnormal emotional state.