On the other hand, long-term psychological distress (7 days following exposure to psychological distress), diminished the aforementioned OCR parameters in PINK1-KO-PBMCs to a similar extent as WT-PBMCs derived from unstressed animals when normalized to mitochondrial content (Fig. 2b–g) but not when normalized to protein content (see Supplementary Fig. S2 in the Supplementary Data file). This evidence concerns the gene PINK1 and Abnormal emotional state.