While many genes implicated in diabetic retinopathy – classically considered a predominantly microvascular complication of diabetes mellitus – were expressed in non-neuronal retinal cell classes (particularly, vascular endothelial cells), a large proportion, such as HS6ST345, DPP1046, and VEGFB, were almost exclusively expressed in RGCs (Fig. 8j). The gene discussed is VEGFB; the disease is diabetic retinopathy.