Of interest, genes on chromosome 8q (MYC), 9q (RNF20, TRAF2), 15q (WDR72, BLM), and 21q (CHODL, SON) demonstrated a significant gain in nHRD pPCL patients compared to nHRD MM patients, which was not observed when comparing the whole pPCL and MM cohort to each other. This evidence concerns the gene SON and Miyoshi myopathy.