Western blotting revealed that knockdown of hsa_circ_0101145 promoted epithelial marker E-cadherin expression, but decreased mesenchymal markers N-cadherin and vimentin expression (Figure 2G–2J), suggesting that depletion of hsa_circ_0101145 inhibited the EMT of HCC cells. The gene discussed is CDH2; the disease is hepatocellular carcinoma.