Vulnerability to heat stress in FTO-antisense knock-down chicks, on the one hand, and increase in fear memory (Widagdo et al., 2016; Walters et al., 2017; Engel et al., 2018) and anxiety-like behavior (Spychala and Rüther, 2019) in Fto-knock-down mice, on the other hands, highlight the role of m6A RNA methylation in different memory-related processes. This evidence concerns the gene FTO and Anxiety.