LAMP5 and leukemia: To reveal the clinical relevance of LAMP5-AS1, we analyzed its expression pattern using a large cohort of clinical samples with and without MLL rearrangements; a significantly higher expression level of LAMP5-AS1 was found in the MLL leukemia patient group than in the MLL-wt leukemia or healthy control sets (p < 0.001) (Fig. 1a; Additional file 1: Table S1).