In addition, FOXP1 has been identified as a critical effector of PRMT5, an arginine methyltransferases regulating proliferation and self-renewal of breast cancer stem cells through a mechanism in which arginine PRMT5 recruitment to FOXP1 promoter facilitates H3K4me3 and H3R2me2 as well as SET1 recruitment [67]. This evidence concerns the gene FOXP1 and breast carcinoma.