Whereas, the TCM from colonic adenocarcinoma significantly inhibited CD54 (p = 0.011), HLA-DR (p = 0.013), CD86 (p = 0.021), CD83 (p = 0.018) and PD-L1 (p = 0.006) compared to LPS-induction in background media alone, cRPMI (+). This evidence concerns the gene CD274 and colon adenocarcinoma.