Secondly, we measured the expression levels of five target genes of PCBP1 (CD44v6, STAT3, MAPK1, ITGB1, DAB2) based on the results of according to the analysis of mRNA sequencing in HCC and tissues and results of previous studies (Additional file 6, Fig. 4a). The gene discussed is ITGB1; the disease is hepatocellular carcinoma.