In our pervious study [16], we systematically determined that the proportion of Th2, Th17, and Treg cells in PBMCs and of their related cytokines IL-4, IL-10, IL-17, IL-23, and TGF-βI in the serum were markedly increased in UCC and CIN patients. This evidence concerns the gene TGFBI and cervical squamous intraepithelial neoplasia.