The levels of the marker for the general activated microglia, CD68, markers for M1 microglia (CD86 and MHC II) and markers for M2 microglia (CD206 and CD163) were all increased in GL261-C glioma tissue than in GL261-eGFP and GL261-vC glioma tissues (Figure 8H-I). This evidence concerns the gene MRC1 and central nervous system cancer.