Moreover, studies of coronary atherosclerosis and abdominal aortic aneurysm showed that miR-103 played a novel role in negatively regulating inflammatory pathways through targeting chemokine (C-C motif) ligand 13 (CCL13) and ADAM metallopeptidase domain 10 (ADAM10) respectively 55,56. Here, ADAM10 is linked to coronary atherosclerosis.