ITGB4 and neoplasm: As shown in Figure 10, we observed that the expression levels of ITGB1 (P < 0.01), LAMB1 (P < 0.01), CD70 (P < 0.01), and CD27 (P < 0.01) were significantly increased in LUAD tumor cells and the expression levels of CXCR5 (P < 0.01), CXCL13 (P < 0.01), ITGB4 (P < 0.01), and CCL5 (P < 0.01) were also increased prominently in tumor T cells.