CXCR3 and CXCR5 (e.g., CXCL10-CXCR3, CXCL11-CXCR3, and CXCL13-CXCR5), which belong to the CXC chemokine receptor family, were found highly expressed in tumor T cells. This evidence concerns the gene CXCR3 and neoplasm.