Besides, as shown in Supplementary Figure 8, we noticed that compared with tumor lung tissues, EPCAM+/FOLR1+ cells had a much larger proportion in normal samples (48.3% vs.3.91%, 65.4% vs.13.3%, and 68.3% vs.1.08%, in CD45- cells respectively), while there are less EPCAM+/FOLR1- cells in normal samples (5.14% vs.72.6 %, 0.70% vs. 58.4%, and 0.83% vs. 55.1%, in CD45- cells respectively). This evidence concerns the gene FOLR1 and neoplasm.