NUCB2 and neoplasm: In survival analyses of ligands highly expressed in LUAD tumor cells, we observed that patients with high expression of CD70 (P = 0.02), CXCL11 (P < 0.001), and LYPD3 (P = 0.03) were related to poorer prognosis while patients with high expression of NUCB2 (P = 0.01) had significantly better prognosis (Figure 6C).