MYC and neoplasm: When compared the pathway expression levels in tumor-derived T cells and non-tumor T cells (Figure 5C), we noticed that tumor-associated increases in disorder of the cell cycle (apoptosis, unfolded protein response, DNA repair, and G2M checkpoint), cell proliferation (myc targets, mtorc1 signaling, and e2f targets), and biomass production (glycolysis and xenobiotic metabolism).