FOXP3 and myeloid sarcoma: Multiple previous studies established the crucial roles of Foxp3+ Treg cells in the protection and recovery from MS and EAE and showed that the absence of Treg cells or their abnormal functions exacerbated the severity of disease both in patients and in animal models of MS [80,81,82,83,84,85,86,87,88,89,90,91,92,93].