The miRNAs miR-146a-5p, -142a-5p and -10a-5p show common increase in the hippocampi of transgenic APP (APPswe/PS1L166P) and TAU (THY-Tau22) mice, and the levels of miR-146a-5p and -142a-5p are also elevated in the post-mortem hippocampal tissue of AD patients [39]. This evidence concerns the gene APP and Alzheimer disease.