POLA2 and glioblastoma: Using the R2: Genomics Analysis and Visualization Platform (http://r2.amc.nl), we examined microarray data from GBM patients provided by the Kawaguchi (GEOID: gse43378) [16], Sun (GEOID: gse4290) [17] and French (GEOID: gse16011) [18] datasets, and found that POLA2 expression is elevated in GBM tumor samples, as compared to normal brain tissue (Figure 1A).