HIP1R and neoplasm: The results revealed that HIP1R mRNA and protein levels were downregulated in primary GC tissues (mRNA: adjacent 34.12 ± 17.013 vs tumor 20.99 ± 12.371, P < .001; Protein: adjacent 3.33 ± 0.200 vs tumor 2.99 ± 0.211, P < .001) (Figure 1B,C).