Symptoms of preeclampsia were also overcome in lentiviral sFlt1-treated mice by concomitant administration of the drug pravastatin [139] and in BPH/5 mice by injection of the drug celecoxib at the time of embryo implantation, which apparently acted by restoring the levels of Cox 2, VEGF, and related angiogenic factors [140]. This evidence concerns the gene VEGFA and preeclampsia.