IGF1 and heart failure: There was no strong evidence for associations between IGF-1 levels and heart failure (OR 1.01 [95% CI 0.97, 1.06]), atrial fibrillation (OR 1.03 [95% CI 0.97, 1.08]) or ischaemic stroke (OR 1.03 [95% CI 0.98, 1.08]) (Fig. 1).