The histological characterization of melanoma was further investigated by immunohistochemistry analysis for Ki-67 staining (control, n = 6; L9Mc SCR, n = 4; L9Mc, n = 4) and for cleaved caspase-3 staining (control, n = 6; L9Mc SCR, n = 5; L9Mc, n = 5). This evidence concerns the gene MKI67 and melanoma.