Lumican and its derived peptides were also demonstrated to inhibit melanoma cell proliferation in vitro (D'Onofrio et al., 2008; Zeltz et al., 2009; Brézillon et al., 2013; Pietraszek et al., 2013; Stasiak et al., 2016; Jeanne et al., 2017). Here, LUM is linked to melanoma.