The exogenous SP-D reduced allergen-induced early airway response, bronchial hyper-responsiveness, blood eosinophilia, and Th2 cytokines in murine models of A. fumigatus induced allergic asthma possibly by reducing eotaxin levels in the lung (Erpenbeck et al., 2006). Here, SFTPD is linked to Increased total eosinophil count.