TRPV1 and hepatocellular carcinoma: In our study, the results of the 20 pairs of HCC and paracancerous tissues for qRT-PCR, as well as 90 pairs HCC biochips for IHC confirmed that all of the F2, GOT2, and TRPV1 genes are significantly and consistently down-expressed in HCC tissues, and this is reconfirmed by three independent microarrays.