The DFS-related multivariate analysis results showed that the expression of 39 genes (ALDOB, APOB, AURKB, C5, CCNF, CD4, CENPJ, CETP, COL18A1, CPT2, DAND5, DNASE1, EBPL, F7, FLT3, G6PD, GNMT, ITGB2, KLRK1, KNG1, LMOD1, NEK2, PCLAF, PER1, PKM, POU2F1, PPAT, PPIA, PRF1, PTPN6, RUNX3, SELP, SLCO1B1, SPPL2A, STAT5A, TCF21, TRPV1, TUSC1, and TYMS) was significantly associated with DFS in HCC patients (p < 0.05, Table 1). The gene discussed is SPPL2A; the disease is hepatocellular carcinoma.