Taurine up-regulated gene 1 (TUG1) is highly expressed in HCC cells and upregulates miR-455-3p at the transcriptional level, thus the TUG1/miR-455-3p/AMPKβ2 axis promotes glycolysis and metastasis by upregulating HK2 (40). The gene discussed is TUG1; the disease is hepatocellular carcinoma.