Nevertheless, only a few potentially useful prognostic biomarkers have been reported for RCC to date; for example, through screening the TCGA database, Han et al. (2017) discovered that numerous protein biomarkers, such as fatty acid synthase (FASN) and AKT3 were prognostic factors for the survival of patients with ccRCC; and using the Oncomine and K-M plotter databases, our previous study reported that several mRNA biomarkers, such as FASN and ATP citrate lyase (ACLY), may be prognostic factors for ccRCC (Zhao et al., 2019). The gene discussed is FASN; the disease is renal cell carcinoma.