AKT1 and nonpapillary renal cell carcinoma: AKT1 was discovered to be a favorable factor in stage I [HR 95% CI = 0.44 (0.24–0.80)], whereas it found to be a poor factor in stage II and III patients with ccRCC [HR 95% CI = 3.00 (0.98–9.20); 2.15 (1.14–4.07), respectively].