Further subgroup analysis found the KRAS mutation was an independent risk factor for the CSS of stage III (HR = 1.28 (95% CI [1.09–1.49]), p < 0.05) and stage IV (HR = 1.14 (95% CI [1.06–1.23]), p < 0.05) CRC patients. Here, KRAS is linked to colorectal carcinoma.