NEIL1 and B-cell acute lymphoblastic leukemia: For instance, a deletion of the NEIL1 gene was found in a case of FL that transformed into a B-cell acute lymphoblastic leukemia (B-ALL) (177), and the expression of NEIL1 mRNA was part of a classifier that distinguished the germinal center B-cell-like (GCB) subtype from the activated B-cell-like (ABC) subgroup of DLBCL, and was associated with disease aggressiveness in the ABC subgroup (178).