PPARG and Sepsis: Zingarelli et al. showed that treatment with PPARγ ligands, 15-deoxy-Delta(12,14)-PGJ(2) (15d-PGJ(2)), and ciglitazone attenuated inflammation, reduced excess neutrophil influx into various organs, decreased hypotension and improved survival through regulation of NF-κB and AP-1 signaling pathways using murine CLP model of sepsis (83).