IL6 and central precocious puberty: We previously observed no detectable induction of a MAP-specific immune responses in CPP at 2 months post-infection when quantifying IgA-, IgG-, and IFNG-secreting cells (34) and in this study we provide additional evidence that only one (IL6) of 23 cytokine genes was modestly upregulated in CPP at 2 months post-infection (Figure 7B).