We observed that in IBD CD4+ T cells, lnc-ITSN1-2 expression was similar (Figure 13A), while IL-23R expression (Figure 13B) was increased in the LV-anti-lnc-ITSN1-2 & LV-IL-23R group compared to the LV-anti-lnc-ITSN1-2 group. This evidence concerns the gene IL23R and inflammatory bowel disease.