To investigate whether stimulation of EGFR signaling could be pro-viral for both αHHV, ARPE-19 cells were infected with cell-free HSV-1.VP16-GFP or VZV.BAC-GFP and at 4 hpi cells were treated with or without EGF and infection frequencies determined at different hpi by flow cytometry. The gene discussed is EGFR; the disease is infection.