This includes the cylindromatous organization with p63+ basal cells from an adenoid cystic carcinoma (ACC, GCRC1828); synaptophysin expression in a neuroendocrine carcinoma (NE, GCRC1979); mucicarmine+ lakes from a mucinous tumor (GCRC2007); loss of E-cadherin in an invasive lobular carcinoma (ILC, GCRC1971); and vimentin+ mesenchymal-like cells dispersed in a chondroid matrix in a metaplastic breast cancer (GCRC1784) (Fig. 1f, Supplementary Fig. 4a). The gene discussed is SYP; the disease is neuroendocrine carcinoma.