VIM and colorectal carcinoma: MiRNAs have been implicated in CRC tumorigenesis and metastasis, and represent effective molecular biomarkers for CRC diagnosis, prognosis, and therapy.6,23 In this study, we found that miR-17-5p expression was significantly down-regulated in primary CRC tissues with metastasis than in those without metastasis in our sequencing data, and its expression was inversely correlated with vimentin expression in CRC tissues and cell lines.